Genentech, a member of the Roche Group, has entered an agreement to acquire Seragon Pharmaceuticals, a privately-held biotechnology company based in San Diego, for $725 million in cash upfront, plus additional payments of as much as $1 billion in potential milestones. Seragon has a portfolio of investigational next-generation oral selective estrogen receptor degraders (SERDs) for the potential treatment of hormone receptor-positive breast cancer.   As much as 60% of breast cancers depend on the ...